Layouts can be flipped and rotated in the Page Editor. First, apply a layout (with or without images) to your page. Click on the general menu icon at the top of the page.
You can swap (flip) the page layout horizontally or vertically, or to rotate the layout 90% clockwise.
A horizontal swap flips the right and left sides of the page.
A vertical swap flips the page top to bottom.
Rotating the page layout turns it 90 degrees clockwise.
Flipping and rotating the layouts does not change the orientation of images within the frames.